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SIDE EFFECTS 5-HTP TYROSINE DOPA-PARADOXICAL REACTIONS 1

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SIDE EFFECTS 5-HTP TYROSINE DOPA-PARADOXICAL REACTIONS

 
Written by: Marty L. Hinz, MD
President Clinical Research
NeuroResearch Clinics, Inc.
Cape Coral, Florida USA Research Office
 
PATIENT HAND OUT
Paradoxical Reactions

   Side effects of 5-HTP tyrosine dopa paradoxical reactions: A “Paradoxical reaction” is where symptoms of serotonin and dopamine neurotransmitter disease such as depression, anxiety, attention deficit ADD ADHD, etc., etc. exacerbate or get worse in the early phases of serotonin and dopamine neurotransmitter treatment as the 5-HTP, tyrosine, levodopa, and cysteine is started or being adjusted. For example, a weight loss person complains of increased hunger, a person with migraine headaches complains of increased headaches, or a person with depression complains of increased depression. Examples are numerous. All related to increased symptoms of serotonin and dopamine neurotransmitter disease such as depression, anxiety, attention deficit ADD ADHD, etc., etc. The knee jerk response of physicians is to lower the dose of 5-HTP, tyrosine, levodopa, and cysteine. This is exactly the opposite of what needs to be done. If you have a person who experiences increased symptoms of serotonin and dopamine neurotransmitter disease such as depression, anxiety, attention deficit ADD ADHD, etc., etc. early on in treatment the proper treatment is to increase the 5-HTP, tyrosine, levodopa, and cysteine dosing to the next step of the serotonin and dopamine neurotransmitter treatment protocol NOT decrease the dose. In decreasing the dose and working up slowly you will subject the person to a situation where they will experience the exacerbation of symptoms for a prolonged period of time and in all probability the person will quit treatment.

  I received a call from a physician who reported that a weight person started the level 1 5-HTP, tyrosine, levodopa, and cysteine dosing and experienced a profound exacerbation of depression. In responding, the physician had changed the 5-HTP, tyrosine, levodopa, and cysteine dosing by significantly lowering the dopamine precursor, while increasing the serotonin precursor with no relief.

  The real problem was the person was experiencing a “paradoxical reaction” - an exacerbation of depression. When starting 5-HTP, tyrosine, levodopa, and cysteine therapy with weight people or other serotonin and dopamine neurotransmitter people, it is not uncommon for a paradoxical reaction to occur in approximately 2 to 4% of people. The proper approach to manage paradoxical reactions is to increase the 5-HTP, tyrosine, levodopa, and cysteine dosing of both the serotonin and dopamine precursors to the next level, then paradoxical symptoms will resolve in 1 to 2 days. Unless guided by serotonin and dopamine urinary neurotransmitter testing in treatment of depression, anxiety, attention deficit ADD ADHD, etc., etc., it is best to use the recommended level changes and not lower the precursor dosing of one system and raise the dosing of the other.

SIDE EFFECTS 5-HTP TYROSINE DOPA 2
 
- Side Effects 5-HTP tyrosine dopa
 
- Side Effects 5-HTP tyrosine dopa serotonin syndrome
 
- Side Effects 5-HTP tyrosine dopa Incidence
 
- Side Effects 5-HTP tyrosine dopa GI upset on startup
 
- Side Effects 5-HTP tyrosine dopa GI upset carbohydrate intolerance
 
- Side Effects 5-HTP tyrosine dopa GI Upset Cysteine
 
- Side Effects 5-HTP tyrosine dopa Activation of drug side effects
 
- Side Effects 5-HTP tyrosine dopa Caused by improper use
 
- Side Effects 5-HTP tyrosine dopa Paradoxical Reactions
 
- Side Effects 5-HTP tyrosine dopa Heart Burn
 
- Side Effects 5-HTP tyrosine dopa Dizziness
 
- Side Effects 5-HTP tyrosine dopa Hypersomnolence
 
 

  When faced with a paradoxical reaction, if you decrease the 5-HTP, tyrosine, levodopa, and cysteine dosing, you will not resolve the paradoxical reaction, you will simply leave your person suffering needlessly and never get to where you need to go. Proper management of a paradoxical reaction is to increase the 5-HTP, tyrosine, levodopa, and cysteine dosing of both the dopamine and serotonin systems.

MORE ON PARADOXICAL REACTIONS

When serotonin and dopamine neurotransmitter precursors 5-HTP, tyrosine, levodopa, and cysteine dosing is started or increased, some people experience an increase in their serotonin and dopamine neurotransmitter disease symptoms such as depression, anxiety, attention deficit ADD ADHD, etc., etc. This is known as a “Paradoxical Reaction.” Some common examples of paradoxical reactions are:

Ř      Depression becomes worse.

Ř      Sleep becomes worse

Ř      The weight loss person’s appetite increases.

Ř        Anxiety becomes worse.

Ř      Migraine headaches become worse.

  Any serotonin or dopamine related neurotransmitter dysfunction disease such as depression, anxiety, attention deficit ADD ADHD, etc., etc. can display a paradoxical reaction during treatment.

  If you encounter a paradoxical reaction in your people, treat by increasing the 5-HTP, tyrosine, levodopa, and cysteine dosing to the next level of treatment. Physicians are trained to decrease or stop prescription serotonin and dopamine reuptake inhibitor drugs if a problem is encountered. This is exactly the opposite of what needs to be done with 5-HTP, tyrosine, levodopa, and cysteine associated paradoxical reactions.  When treating with 5-HTP, tyrosine, levodopa, and cysteine, decreasing the dose and then bringing it up slowly will greatly prolong the time that people experience a prolonged exacerbation of symptoms, which is the wrong approach.

  In general, paradoxical reactions occur in the first week or two of serotonin and dopamine neurotransmitter treatment. However, in Parkinson people, it is not uncommon to see paradoxical serotonin and dopamine neurotransmitter reactions occur after the person has been treated for several weeks and dopamine is ready to inflect into the phase 3 serotonin and dopamine neurotransmitter therapeutic range. While this primarily happens with Parkinson people, it can happen later in treatment in other serotonin and dopamine neurotransmitter people as well.

  Paradoxical reactions indicate a need to increase the 5-HTP, tyrosine, levodopa, and cysteine dosing. When obtaining serotonin and dopamine urinary neurotransmitter testing in treatment of depression, anxiety, attention deficit ADD ADHD, etc., etc. on a person, if you spot a paradoxical reaction, simply increase the 5-HTP, tyrosine, levodopa, and cysteine dosing. Do not wait for the results of serotonin and dopamine urinary neurotransmitter testing in treatment of depression, anxiety, attention deficit ADD ADHD, etc., etc. to be returned.

Side effects of 5-HTP tyrosine dopa paradoxical reactions

 
 
 
SIDE EFFECTS 5-HTP TYROSINE DOPA-PARADOXICAL REACTIONS
 
Side effects of 5-HTP tyrosine dopa paradoxical reactions
 
SIDE EFFECTS

  In taking 5-HTP, tyrosine, levodopa, and cysteine there is no side effect that should require stopping on a permanent basis if managed properly. At the left links to management strategies and person hand outs relating to side effects.

 
 

Side effects of 5-HTP tyrosine dopa paradoxical reactions

 
 
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