Organic cation transporter neurotransmitter optimization-Source of urinary neurotransmitters

NeuroResearch Clinics relies exclusively on DBS Labs for urinary serotonin and dopamine neurotransmitter testing in natural treatment of disease. DBS Labs is directed by Tom Uncini, MD hospital based pathologist who is dual board certified in laboratory medicine. Dr. Uncini is the medical director of two hospital labs, University of Minnesota Medical Center Mesabi in Hibbing, MN and Cook Hospital in Cook, MN. Dr. Uncini is also on the faculty of the University of Minnesota Medical School. The urinary neurotransmitter testing produced by DBS Labs is of hospital caliber. Between Dr. Uncini and his lab manager there are over 50 years of hospital based laboratory experience.

The experience and credentials of the people running DBS Labs stand in stark contrast to the other labs out there attempting to do urinary neurotransmitter testing. Other laboratories have no hospital based board certified laboratory medicine pathologist running the lab, no license to practice medicine, no hospital privilege affiliation, no clinic, no patients, and have never treated one patient in clinic. Yet some are holding out that they have the expertise to tell doctors how to treat their patients when the urinary neurotransmitter testing results are reported back to the doctor. This may explain why the testing results of these labs do not correlate when the same sample is run on split sample testing by DBS Labs and the non-MD lab. These non-MD labs are the labs that are recommending and inducing licensed medical doctors to get "baseline urinary neurotransmitter testing" prior to treatment even though there is no correlation between testing prior to and once taking amino acid precursors.

Pike Lake Duluth photo by Amy Gunthert

Organic cation transporter neurotransmitter optimization-SOURCE OF URINARY NEUROTRANSMITTERS

neurotransmitter testing-SOURCE OF URINARY NEUROTRANSMITTERS

Written by: Marty L. Hinz, MD

President Clinical Research

NeuroResearch Clinics, Inc.

Cape Coral, Florida USA Research Office

neurotransmitter testing-SOURCE OF URINARY NEUROTRANSMITTERS

	The concern here is the fact that there are non-MD labs attempting to sell urinary neurotransmitter testing and in the process are promoting the idea serotonin, dopamine, norepinephrine, and epinephrine found in the urine are neurotransmitters that are simply filtered by the kidneys and excreted in the urine. The scientific literature reads itself on this on, the neurotransmitters found in the urine are neurotransmitters synthesized by the kidneys then either excreted into the urine or secreted into the system via the renal vein.
Urine Serotonin 1
Urine Serotonin 2
Urine Serotonin 3
Urine Serotonin 4
Urine Serotonin 5

Urine Dopamine 1
Urine Dopamine 2
Urine Dopamine 3
Urine Dopamine 4

Norepinephrine 1

Urine Epinephrine 1

Urinary neurotransmitter testing of serotonin and dopamine DOES NOT:

Ø Have any value in baseline testing prior to treatment with amino acid precursors 5-HTP, tyrosine, levodopa, tryptophan, or cysteine

Ø Correlate with serotonin and dopamine levels found in the brain (central nervous system)

Ø Correlate with peripheral nervous system serotonin and dopamine levels

Ø Correlate with serotonin and dopamine neurotransmitter illnesses caused by low levels of neurotransmitter molecules (serotonin and dopamine)

Ø Have the ability to diagnose disease associated with low levels of serotonin and dopamine such as depression, anxiety, attention deficit ADD ADHD, etc.

Ø Are of no value in determining initial 5-HTP, tyrosine, levodopa, tryptophan, or cysteine dosing to be used in treatment.

Ø Do not automatically increase in the urine as increasingly high doses of amino acid precursors are given.

Ø Are not serotonin and dopamine that have been simply filtered by the kidney and excreted into the urine. The serotonin and dopamine found in the urine were synthesized by the kidneys.

- neurotransmitter testing

- neurotransmitter testing-In depth

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- neurotransmitter testing-Blood brain barrier

- neurotransmitter testing-Collection time

- neurotransmitter testing-Quality control

- neurotransmitter testing-Quality assurance

- neurotransmitter testing-Reference ranges

- neurotransmitter testing-Flawed results

- neurotransmitter testing-Julia Ross

- neurotransmitter testing-Baseline testing

- neurotransmitter testing-3 phase dosing versus 3 phase response

The University of Minnesota Medical School neurotransmitter testing paper.

FROM PEER REVIEWED LITERATURE

With simultaneous administration of serotonin and dopamine amino acid precursors, three phases of urinary neurotransmitter response have been identified on laboratory assay of the urine. The three phases of response apply to both serotonin and dopamine. In all the life forms tested that have kidneys along with serotonin and catecholamine systems, the three phases of urinary neurotransmitter response exist.⁴⁰ In reviewing the literature it would appear that the 3 phase of urinary response to neurotransmitters were present in previous writings but were not identified as such. For example, a 1999 article notes that administration of L-dopa can increase urinary dopamine levels (phase 3) and decrease urinary serotonin levels (phase 1).

Ingrid Kohlstadt, MD Johns Hopkins, Hinz, M. Depression in I. Kohlstadt (ed.)

Food and Nutrients in Disease Management (CRC Press, 2009)

neurotransmitter testing-SOURCE OF URINARY NEUROTRANSMITTERS

THE ONLY URINARY SEROTONIN AND DOPAMINE CORRELATION WE KNOW OF IS:

Urinary serotonin and dopamine: When in the serotonin and dopamine are in the therapeutic range AND phase 3 Response it correlates with resolution of disease symptoms and optimal function of the system.

neurotransmitter testing-SOURCE OF URINARY NEUROTRANSMITTERS

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