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NeuroResearch Clinics relies exclusively on DBS Labs for urinary serotonin and dopamine neurotransmitter testing in natural treatment of disease. DBS Labs is directed by Tom Uncini, MD hospital based pathologist who is dual board certified in laboratory medicine. Dr. Uncini is the medical director of two hospital labs, University of Minnesota Medical Center Mesabi in Hibbing, MN and Cook Hospital in Cook, MN. Dr. Uncini is also on the faculty of the University of Minnesota Medical School. The urinary neurotransmitter testing produced by DBS Labs is of hospital caliber. Between Dr. Uncini and his lab manager there are over 50 years of hospital based laboratory experience.

  The experience and credentials of the people running DBS Labs stand in stark contrast to the other labs out there attempting to do urinary neurotransmitter testing. Other laboratories have no hospital based board certified laboratory medicine pathologist running the lab, no license to practice medicine, no hospital privilege affiliation, no clinic, no patients, and have never treated one patient in clinic. Yet some are holding out that they have the expertise to tell doctors how to treat their patients when the urinary neurotransmitter testing results are reported back to the doctor. This may explain why the testing results of these labs do not correlate when the same sample is run on split sample testing by DBS Labs and the non-MD lab. These non-MD labs are the labs that are recommending and inducing licensed medical doctors to get "baseline urinary neurotransmitter testing" prior to treatment even though there is no correlation between testing prior to and once taking amino acid precursors.

Pike Lake Duluth photo by Amy Gunthert  
 

Organic cation transporter neurotransmitter optimization-BASELINE TESTING 1

Organic cation transporter neurotransmitter optimization-BASELINE TESTING
Contact us or find a caregiver using this approach.
 

neurotransmitter testing-BASELINE TESTING

Written by: Marty L. Hinz, MD
President Clinical Research
NeuroResearch Clinics, Inc.
Cape Coral, Florida USA Research Office
 
neurotransmitter testing-BASELINE TESTING
 
 

  Medical schools and medical doctors directing medical labs know that baseline urinary neurotransmitter testing prior to starting neurotransmitter treatment is of no value. Tom Uncini, MD dual board certified hospital based laboratory pathologist and his company DBS Labs have been waiting several years for the non-MD labs to catch up with current science. All labs other than DBS advocate getting a baseline test prior to starting neurotransmitter treatment, these are the biochemist labs with no medical license to care for patients. The of practice baseline neurotransmitter testing does nothing to help the patient get better it only lines the bank account with money of those that recommend it. The "baseline urinary neurotransmitter testing" approach is suboptimal and in most cases achieves no relief of symptoms.

  Serotonin and dopamine baseline urinary neurotransmitter testing of the caliber found in hospitals has no correlation with testing once the person is taking 5-HTP, tyrosine, levodopa, and cysteine. The only advocates we have seen of serotonin and dopamine baseline urinary neurotransmitter testing appear to be labs with no board certified hospital based laboratory pathologist (MD) in charge, where almost all baseline urinary neurotransmitter testing results returned show serotonin to be low or in the low end of the reference range.

BASELINE TESTING-IF IT IS NOT DIAGNOSTIC WHY DO IT?

  At every AMA continuing medical education conference this year are physicians who report they have tried using the baseline serotonin and dopamine urinary neurotransmitter testing prior to treatment with their patients. The results reported are very uniform - almost none of the patients treated under the approach of getting baseline testing prior to treated showed improvement of symptoms.

  Serotonin and dopamine baseline urinary neurotransmitter testing prior to treatment does not indicate what the dosing level of 5-HTP, levodopa, and tyrosine should be, nor does it they tell how well a person is going to respond to treatment with 5-HTP, levodopa, and tyrosine. Therefore, baseline serotonin and dopamine neurotransmitter levels are not useful when deciding how to best treat a person with  5-HTP, levodopa, and tyrosine. In close examination of DBS Labs data in of people with and without neurotransmitter disease it is apparent that both groups virtually all have the same urinary serotonin and dopamine levels prior to starting treatment.

- neurotransmitter testing

- neurotransmitter testing-In depth

- neurotransmitter testing-Source of urinary neurotransmitters

- neurotransmitter testing-Blood brain barrier

- neurotransmitter testing-Collection time

- neurotransmitter testing-Quality control

- neurotransmitter testing-Quality assurance

- neurotransmitter testing-Reference ranges

- neurotransmitter testing-Flawed results

- neurotransmitter testing-Julia Ross

- neurotransmitter testing-Baseline testing

- neurotransmitter testing-3 phase dosing versus 3 phase response

 

 
 
 
 
 
 
 
 

The University of Minnesota Medical School neurotransmitter testing paper.

FROM PEER REVIEWED LITERATURE

The novel observations observed in this study include the absence of a consistent relationship between ingested 5-HTP and urinary serotonin excretion and the unexpected influence of Tyrosine to reduce urinary dopamine excretion.  The description of the three phases demonstrating the relationship between 5-HTP and urinary serotonin excretion is also novel and probably is a reflection of serotonin reabsorption in the kidney.  The consistent and statistically discernable ability of Tyrosine to dampen fluctuations in urinary dopamine excretion is also noteworthy.  These processes might be reflective of similar processes occurring in other organs.

Both stimulatory and inhibitory effects of dietary 5 HydroxyTryptophan and Tyrosine on urinary excretion of serotonin and dopamine in a large human population

George J. Trachte, Thomas Uncini and Marty Hinz, Department of Physiology and Pharmacology, University of MN Medical School

 
 

neurotransmitter testing-BASELINE TESTING

TRUE STORY OF BASELINE neurotransmitter testing

   One physician reported he had treated over 100 people with the baseline neurotransmitter testing approach and, “none got better”. The real question is, “Why would you treat over 100 people before deciding the approach did not work?”

BASELINE TESTING FROM THE LITERATURE

Depression in I. Kohlstadt (ed.) Food and Nutrients in Disease Management (CRC Press, 2009)

VI: PERSON EVALUATION, SEROTONIN AND DOPAMINE urinary neurotransmitter testing in treatment.

Full text of the Johns Hopkins writing on urinary neurotransmitters and depression

"Serotonin and dopamine baseline urinary neurotransmitter testing" in treatment prior to 5-HTP, tyrosine, and/or dopa therapy is of no value. There is no correlation between baseline serotonin and dopamine urinary neurotransmitter testing once the person is taking 5-HTP, tyrosine, and/or dopa. It is not necessary or even useful to measure "Serotonin and dopamine baseline urinary neurotransmitter testing prior to treatment."

Urinary monoamine neurotransmitter molecules (serotonin and dopamine) do not cross the blood brain barrier.  Urinary monoamines serotonin, dopamine neurotransmitter molecules are not serotonin, dopamine neurotransmitter molecules filtered by the glomerulous of the kidneys and excreted into the urine.  They are urinary serotonin, dopamine neurotransmitter molecules that are synthesized by the kidneys and excreted into the urine or secreted into the system via the renal veins. With simultaneous administration of serotonin and dopamine precursors 5-HTP, tyrosine, and/or levodopa, three phases of serotonin and dopamine urinary neurotransmitter testing response  have been identified on laboratory assay of the urine.  The three phases of response apply to both serotonin and dopamine.  Serotonin and dopamine urinary neurotransmitter testing results in all life forms that have kidneys along with serotonin and catecholamine systems, the three phases of serotonin, dopamine urinary neurotransmitter response were present in previous writings but were not identified as such. For example, a 1999 article notes that administration of dopa can increase urinary dopamine levels (neurotransmitter phase 3) and decrease urinary serotonin levels (neurotransmitter phase 1).

neurotransmitter testing-BASELINE TESTING

 
 
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