Organic cation transporter neurotransmitter optimization-3 phase dosing versus 3 phase response

NeuroResearch Clinics relies exclusively on DBS Labs for urinary serotonin and dopamine neurotransmitter testing in natural treatment of disease. DBS Labs is directed by Tom Uncini, MD hospital based pathologist who is dual board certified in laboratory medicine. Dr. Uncini is the medical director of two hospital labs, University of Minnesota Medical Center Mesabi in Hibbing, MN and Cook Hospital in Cook, MN. Dr. Uncini is also on the faculty of the University of Minnesota Medical School. The urinary neurotransmitter testing produced by DBS Labs is of hospital caliber. Between Dr. Uncini and his lab manager there are over 50 years of hospital based laboratory experience.

The experience and credentials of the people running DBS Labs stand in stark contrast to the other labs out there attempting to do urinary neurotransmitter testing. Other laboratories have no hospital based board certified laboratory medicine pathologist running the lab, no license to practice medicine, no hospital privilege affiliation, no clinic, no patients, and have never treated one patient in clinic. Yet some are holding out that they have the expertise to tell doctors how to treat their patients when the urinary neurotransmitter testing results are reported back to the doctor. This may explain why the testing results of these labs do not correlate when the same sample is run on split sample testing by DBS Labs and the non-MD lab. These non-MD labs are the labs that are recommending and inducing licensed medical doctors to get "baseline urinary neurotransmitter testing" prior to treatment even though there is no correlation between testing prior to and once taking amino acid precursors.

Pike Lake Duluth photo by Amy Gunthert

Organic cation transporter neurotransmitter optimization-3 PHASE DOSING VERSUS 3 PHASE RESPONSE

Written by: Marty L. Hinz, MD

President Clinical Research

NeuroResearch Clinics, Inc.

Cape Coral, Florida USA Research Office

neurotransmitter testing-three PHASE DOSING VERSUS three PHASE RESPONSE

There are companies operated by PhD biochemists that promote the idea that baseline urinary neurotransmitter testing then recommend giving nutrients in "three phases" such as the "initial phase, the "restoration phase" and the "maintenance phase". NeuroResearch Clinics has moved urinary neurotransmitter testing far beyond the baseline urinary neurotransmitter testing crowd. With the realization that "three phases of urinary serotonin and dopamine" exist with administration of the nutrients 5-HTP, tyrosine, levodopa, and cysteine. A whole new world beyond baseline neurotransmitter testing has opened up. Confusion on the street exits between:

The "three phases of nutrient dosing"

The "three phases of urinary serotonin and dopamine response"

The confusion has lead to comments such as, "They are both using that three phase stuff and doing the same thing." When in fact these are two completely different concepts. Make no mistake the "baseline neurotransmitter testing" approach is suboptimal in treatment of symptoms. In analysis of the "three phase urinary serotonin and dopamine" approach of NeuroResearch Clinics 100% of people with depression, anxiety, attention deficit ADD ADHD, etc. and a number of other diseases will achieve complete relief of symptoms. Whereas with the "baseline neurotransmitter testing" approach many doctors have reported that very few or none of their patients actually got relief of symptoms.

neurotransmitter testing-three PHASE DOSING VERSUS three PHASE RESPONSE

- neurotransmitter testing

- neurotransmitter testing-In depth

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- neurotransmitter testing-Collection time

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- neurotransmitter testing-Flawed results

- neurotransmitter testing-Julia Ross

- neurotransmitter testing-Baseline testing

- neurotransmitter testing-three phase dosing versus three phase response

University of Minnesota Medical School neurotransmitter testing paper.

FROM PEER REVIEWED LITERATURE

The 5-HTP suppressed urinary serotonin excretion in the phase 1 samples and augmented excretion in the phase three samples. The phase 2 samples had extremely low urinary serotonin levels and the concentrations did not fluctuate in response to alterations in 5-HTP dosing. Phase 2 values were significantly lower than urinary serotonin levels in either phase 1 or phase three samples (p < 0.0001) and the slopes of all three curves differed significantly (p = 0.0022). Urinary serotonin excretion in the absence of 5-HTP dosing was statistically higher in the phase 1 samples than either of the other two groups. This finding is consistent with the phase 1 group demonstrating large declines in urinary serotonin levels in response to increased administration of 5-HTP

Both stimulatory and inhibitory effects of dietary 5 HydroxyTryptophan and Tyrosine on urinary excretion of serotonin and dopamine in a large human population

George J. Trachte, Thomas Uncini and Marty Hinz, Department of Physiology and Pharmacology, University of MN Medical School

neurotransmitter testing-three PHASE DOSING VERSUS three PHASE RESPONSE

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