REUPTAKE INHIBITORS, are used to treat depression, attention deficit, OCD, and a host of other disease. As noted in the antidepressants section of this web site the odds of drug side effects developing in depression treatment are greater than getting relief of symptoms greater than placebo.

Neurotransmitter levels in the brain that are not high enough cause disease. In reviewing drug side effects the reuptake inhibitor side effect of depleting neurotransmitters is unique. These are the only drugs in medicine where drug side effects make the cause of the problem worse.

Drugs that work with neurotransmitters do not work if there is not enough neurotransmitters in the system to work. When the reuptake inhibitor drug quits working it is because the drug has just depleted the neurotransmitter levels below levels needed to keep the drug working. Drugs are commonly viewed as having two categories of drug side effects, reversible and irreversible. Drug side effects involving depletion of neurotransmitters is reversible if proper levels of nutrients are given. With severe neurotransmitter depletion the patient may become suicidal and commit suicide an irreversible display of drug side effects.

In the right column is a sampling of reuptake inhibitor drugs with prescribing information. Click on each, at the top is a drug side effects warning of the risk of "clinical worsening" and "suicide" developing. When the drug burns out the neurotransmitters enough the clinical condition worsens. With severe neurotransmitters depletion by the drug the patient may become suicidal. Most doctors do not understand how these drug side effects are caused by the drugs.

One of the basic foundations of medicine is, "First do not harm". In other words, "don't make the disease worse or create new problems". If during treatment the doctor makes the cause of the problem worse, the doctor has just violated this basic foundation of medicine.

- Neurotransmitter depletion

- Neurotransmitter depletion drugs deplete neurotransmitters

- Neurotransmitter depletion drugs cause suicide

- Neurotransmitter depletion 5-HTP depletes dopamine

- Neurotransmitter depletion L-dopa depletes serotonin

- Neurotransmitter depletion Tyrosine depletes serotonin

- Neurotransmitter depletion-Balance between serotonin and dopamine

- Neurotransmitter depletion-The NeuroResearch serotonin and dopamine balanced approach

The reuptake inhibitor drugs deplete neurotransmitter levels if given with properly balance nutrients. Herein lies the problem, the standard approach in medicine in treating depression with reuptake inhibitor drugs is not proper. The current treatment approach with these drugs facilitates neurotransmitter depletion making the cause of the problem worse, neurotransmitter levels that are not high enough to keep disease symptoms under control.

Drug Side Effects

HOW DRUGS DEPLETE NEUROTRANSMITTERS

The following is a discussion of what NeuroResearch Clinics has been teaching since 1998 on drug side effects. In 2007 the following pictures were posted on the "National Institute of Drug Abuse" web site discussing how reuptake inhibitors drugs deplete neurotransmitters. The National Institute of Drug Abuses explanation of how reuptake inhibitor drugs deplete neurotransmitters it is the exact same explanation NeuroResearch Clinics formulated in 1998. Following pictures are courtesy of the National Institute of Drug Abuse.

For people suffering with neurotransmitter disease synaptic neurotransmitter levels are below the levels needed to prevent symptoms of disease. The picture below illustrates not enough neurotransmitters (the red triangles) in the synapse to keep disease symptoms under control.

drug side effects

Serotonin, dopamine, and norepinephrine reuptake inhibitor drugs, as well as amphetamines, and cocaine, block the reuptake of the neurotransmitter molecules back into the presynaptic neuron. This leads to a decrease in presynaptic neuron neurotransmitter levels (where the neurotransmitter is safe from enzymatic breakdown). The blocking of neurotransmitter reuptake increases the neurotransmitter levels in the synapse and increases the enzymatic metabolism (breakdown) by the MAO and COMT enzymes. If proper levels of balanced nutrients are not given with these drugs the neurotransmitters are depleted by their increased exposure to the enzymes that break them down.

The net effect of neurotransmitter exposure to MAO and COMT enzymatic metabolism is how drugs deplete neurotransmitters. The neurotransmitter molecules do not cross the blood brain barrier. The only way to increase neurotransmitter levels in the brain in order to prevent the depletion of neurotransmitter levels by drugs is to provide properly balanced 5-HTP, tyrosine, levodopa, tryptophan, and cysteine, which crosses the blood brain barrier then are synthesized into new neurotransmitter molecules in the brain. With proper nutrient administration neurotransmitter levels in the brain are elevated to levels above what is needed to keep symptoms under control.

Drug Side Effects

Links to Information

Prozac Drug Side Effects

Zoloft Drug Side Effects

Lexapro Drug Side Effects

Effexor Drug Side Effects

Wellbutrin Drug Side Effects

Paxil Drug Side Effects

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Drug Side Effects