Depression 5-HTP L-dopa Monoamine Neurotransmitter Metabolism
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Depression 5-HTP L-dopa Monoamine Neurotransmitter Metabolism

 
 
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Depression 5-HTP L-dopa Monoamine Neurotransmitter Metabolism-research

 
 
Depression 5-HTP L-dopa Monoamine Neurotransmitter Metabolism

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Depression 5-HTP L-dopa Monoamine Neurotransmitter Metabolism

Written by: Marty L. Hinz, MD
President Clinical Research
NeuroResearch Clinics, Inc
Cape Coral, Florida USA Research Office
 

POSTED by J1237 Jan 31, 2009 06:59PM: I have suffered with severe depression and anxiety for about 10 years.  I was very, extremely skeptical about the NeuroResearch formulas after having been on a myriad of antidepressant SSRI's.  I thought it was just a money making scheme and I was scared. Let me just say that I'm glad I did my research and I'm glad I tried it because it has made a WORLD OF DIFFERENCE.

 

  Depression 5-HTP L-dopa Monoamine Neurotransmitter Metabolism

  The Monoamine Oxidase (MAO) and Catecholamine-O-Methyl Transferase (COMT) enzymes metabolize serotonin and the catecholamines, as illustrated in the kidney in figure 4 bottom left.12 The implications are profound.  The levels of these two enzyme systems are not static; they fluctuate in response to changing neurotransmitter levels.  When neurotransmitter levels are increased, enzymatic activity also increases.

  If you administer L-dopa or 5-HTP, the activity of MAO and COMT increases due to the increase in dopamine or serotonin levels respectively.  The problem occurs when L-dopa is administered without 5-HTP, both dopamine and serotonin will be subjected to increases in metabolism by these two enzyme systems.  However, serotonin will 

Depression 5-HTP L-dopa Monoamine Neurotransmitter Metabolism

not experience an increase in production, which leads to further depletion.  The same rule is true of 5-HTP administered without the use of dopamine precursors.  The bottom line is that the administration of 5-HTP or L-dopa that is unopposed or improperly balanced with the amino acid precursors of the other system will deplete the other system as a result of the increased metabolism of MAO and COMT, decreased synthesis, and uptake competition (as covered in the next section).

Depression 5-HTP L-dopa Monoamine Neurotransmitter Metabolism

  Its no secret, NeuroResearch Clinics uses the nutrients 5-HTP, tyrosine, levodopa, and cysteine to treat medical patients in order to get these results. Proper use of these simple ingredients in medical treatment is not simple. From time to time a patient will say, "Why do I want to take that, I can go to a health food store and buy it?" People off the street buying in a health food store is like going to an art store and buying a bunch of oil paints then going home and expecting to paint like a mater artist even though there was no previous painting experience. These nutrients have tremendous potential due to their chemical properties. This potential is only fully realized in the hands of the trained professional using neurotransmitter testing. Treatment is not just giving a nutrient pill, it is the whole medical management approach doctors are trained in to insure that that treatment is on track in order to get symptoms under control.

The Peer Reviewed Research of NeuroResearch Clinics

  The neurotransmitter treatment research findings of NeuroResearch Clinics have not been ignored. The University of Minnesota Medical School is writing a series of papers on the neurotransmitter testing research of NeuroResearch Clinics. The first of a series of papers by University of Minnesota Medical School based on the neurotransmitter testing research of NeuroResearch was published in "NeuroPsychiatric Disease and Treatment" May 1, 2009. Ingrid Kohlstadt, MD of Johns Hopkins in her new medical text book released February 7, 2009 included a chapter on depression written by Marty L. Hinz, MD  President Clinical Research NeuroResearch Clinics outlining in depth the proper use of amino acids and neurotransmitter testing in treatment of depression.

University of Minnesota Medical School neurotransmitter testing paper on the research of NeuroResearch Clinics.

 

The medical text book chapter on depression written by Marty L. Hinz, MD-Ingrid Kohlstadt, MD editor-Johns Hopkins released February, 7, 2009

 
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Depression 5-HTP L-dopa Monoamine Neurotransmitter Metabolism