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ANTIDEPRESSANTS
DEPLETE
NEUROTRANSMITTERS |
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ANTIDEPRESSANTS
DEPLETE
NEUROTRANSMITTERS |
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ANTIDEPRESSANTS
DEPLETE
NEUROTRANSMITTERS
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Web site
written by: |
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Marty L. Hinz, MD |
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President
Clinical
Research |
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NeuroResearch
Clinics,
Inc. |
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Cape Coral, Florida USA Research Office |
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Antidepressants
deplete
neurotransmitters: Neurotransmitter levels in the brain that are not high
enough cause disease. Antidepressants that work by moving
neurotransmitters from one place to another (the
reuptake in inhibitor antidepressants) set up circumstances
where the antidepressants deplete neurotransmitters in the
brain making the cause of
the disease worse while attempting to make symptoms
of disease better. These antidepressants antidepressants known as
"reuptake inhibitors" are used to treat depression,
attention deficit (ADHD and ADD), anxiety, and a
host of other diseases. A list of reuptake inhibitor
antidepressants can be found in the lower left column of this
web page.
Usually the first thing seen when antidepressants
deplete neurotransmitters is that the drug quits
working and the symptoms of disease return.
Antidepressants
that work with neurotransmitters do not work if
there is not enough neurotransmitters to work with
and when the drug quits working it is because the
drug has just depleted the neurotransmitter levels
below what is needed to keep the drug working. When
these antidepressants deplete neurotransmitters most
doctors do not know what they are looking at and
even fewer doctors know how to manage the situation
when antidepressants deplete neurotransmitters properly.
In
treating disease one of the
basic foundations of medicine is, "First do not harm".
In other words, "don't make the disease worse or create new
problems". If while treating the doctor makes the
cause of the problem worse, the doctor has just violated this basic
foundation of medicine. The reuptake inhibitor antidepressants used to treat depression, anxiety, attention deficit ADD ADHD,
etc. antidepressants as well as 5-HTP, tyrosine, levodopa, and
cysteine all deplete serotonin, dopamine, or norepinephrine
neurotransmitter levels if not used properly. Herein lies
the problem, the standard approach in medicine in treating
depression with reuptake inhibitor antidepressants, 5-HTP, tyrosine,
levodopa, tryptophan, and cysteine is not proper. The current
treatment approach in medicine with these antidepressants and
nutrients facilitates depletion of serotonin, dopamine, or
norepinephrine making the cause of the disease worse, neurotransmitter
levels that are not high enough to keep disease symptoms under
control.
HOW ANTIDEPRESSANTS DEPLETE NEUROTRANSMITTERS
Since
1998 NeuroResearch Clinics has been teaching doctors how
reuptake inhibitor antidepressants deplete neurotransmitters and how
to deal with the problem properly. The following discussion is what
we have been teaching. In 2007 NeuroResearch Clinics found
the following pictures on the "National Institute of Drug Abuse" web site
in support of a discussion of how reuptake inhibitors
antidepressants deplete neurotransmitters. The National Institute of Drug
Abuses explanation of how reuptake inhibitor antidepressants deplete
neurotransmitters
it is the exact same explanation we formulated in 1998 and
have been using since. Following
pictures are courtesy of the National Institute of Drug Abuse. |
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For
people suffering with
neurotransmitter disease
synaptic
neurotransmitter levels are below the levels needed to
prevent symptoms of disease.
The picture below illustrates not enough
neurotransmitters (the red triangles) in the synapse to
keep disease symptoms under control.
Serotonin, dopamine, and norepinephrine reuptake
inhibitor antidepressants, as well as
amphetamines, and cocaine, block the reuptake of
the neurotransmitter
molecules
back
into the presynaptic neuron. This leads to a
decrease in presynaptic neuron neurotransmitter levels
(where the neurotransmitter is safe from
enzymatic breakdown). The blocking of
neurotransmitter reuptake increases the
neurotransmitter levels in the synapse and increases
the enzymatic metabolism (breakdown) by
the MAO and COMT enzymes. If proper levels of
balanced nutrients are not given with these
antidepressants the neurotransmitters are depleted by
their increased exposure to the enzymes that
break them down.
Overtime, the net effect of neurotransmitter exposure to
MAO and COMT enzymatic metabolism is a situation where
antidepressants deplete neurotransmitters. The neurotransmitter
molecules
do not
cross the blood brain barrier. Therefore, the only way
to increase neurotransmitter levels in the brain in
order to prevent the depletion of neurotransmitter levels by
antidepressants is to provide
properly balanced
5-HTP, tyrosine,
levodopa, tryptophan, and cysteine, which crosses the blood brain barrier then are
synthesized into new serotonin, dopamine, and
norepinephrine
molecules
in the
brain. If nutrients are administered properly
neurotransmitter levels in the brain are easily elevated
to levels far above what is needed to keep symptoms
under control.
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ANTIDEPRESSANTS
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THE
NEURORESEARCH CLINICS APPROACH TO DEPRESSION TREATMENT
It
is
no secret NeuroResearch Clinics uses
the nutrients 5-HTP, tyrosine, levodopa,
and
cysteine in conjunction with
neurotransmitter testing as
indicated to treat medical patients
in order to get the results
documented by our doctors, Proper
use these simple
ingredients in medical treatment is not simple.
From time to time a patient will
say, "Why do I want to take that, I
can go to a health food store and
buy it?" People off the street
buying in a health food store is like going to an art
store and buying a bunch of oil
paints then going home and expecting
to paint like a mater artist even
though there was no previous
painting experience. Having been in
medicine since 1972 I can firmly
state that use of 5-HTP, tyrosine,
levodopa, and cysteine, in medical
clinics, with urinary
neurotransmitter testing is some of
the most sophisticated medical
treatment in medicine.
These nutrients have tremendous
potential due to their chemical
properties. The potential is only
fully realized in the hands of the
trained professional. Treatment is
not just giving a nutrient pill, it is the whole medical approach
doctors are trained in to manage the
disease properly and make sure that
that the whole treatment plan is on
track to get symptoms under control. |
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ANTIDEPRESSANTS
DEPLETE
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