NeuroResearch Clinics: neurotransmitter testing
This is an
overview of how neurotransmitter testing found
its place in the research of NeuroResearch
Clinics. For an in depth discussion of
neurotransmitter testing click on the
"neurotransmitter testing" link in the
black colored column to the left.
The only viable option for clinical
neurotransmitter testing application
is urinary neurotransmitter testing. Due to
limitations other neurotransmitter testing methods involving
serum (blood), saliva, and central spinal fluid
are not a viable option in the clinic.
There are two types of labs in the world:
-
neurotransmitter testing preformed by laboratories directed by
licensed hospital based medical doctors who are board certified in laboratory
medicine.
-
neurotransmitter testing performed by Laboratories operated by
chemists with no medical license.
Early on NeuroResearch Clinics contracted for
neurotransmitter testing laboratories from
laboratories directed by chemists. This involved
multiple laboratories. Reported laboratory
results from the chemist laboratories caused neurotransmitter testing confusion. The
neurotransmitter testing lab data
being reported was so flawed that it was
discarded. The chemist labs expounded the belief that:
-
serotonin and
dopamine found in the urine on
neurotransmitter testing is
simply filtered by the glomerulous of kidneys
excreted into the urine
-
serotonin and
dopamine cross the blood brain barrier
therefore the serotonin and dopamine in the
urine on neurotransmitter testing is
serotonin and dopamine that was in the brain.
-
baseline
neurotransmitter testing is needed prior to
starting treatment.
On review of the
scientific literature these assertions are not
true. The following is true:
-
serotonin and dopamine do not cross the
blood brain barrier
-
serotonin and
dopamine found in the urine on
neurotransmitter testing are serotonin and
dopamine synthesized by the kidney
then excreted into the urine, virtually
none of the serotonin and dopamine filtered by the
kidneys make it to the urine, they are metabolized
by the kidney.
-
baseline
neurotransmitter testing prior to treatment
is of no value and does not correlate with
neurotransmitter testing once the patient is
taking significant amounts of nutrients.
It was also found that the neurotransmitter testing being reported by chemist labs were so
flawed that results were discarded from research
considerations. How was this realized? In 2003
Tom Uncini, MD hospital based dual board
certified laboratory pathologist opened DBS
Labs. It took Dr. Uncini 13 months to get
precision and accuracy studies for
neurotransmitter testing perfected. Once
perfected statistical analysis revealed that the
neurotransmitter testing of the chemist labs had
no correlation with the results being reported
by Tom Uncini, MD hospital based dual board
certified pathologist. NeuroResearch Clinics determined
that Dr. Uncini's lab was valid and went
forward. By 2005 NeuroResearch Clinics defined
the ground breaking concept of "the three phase response
of urinary neurotransmitters during administration of
nutrients".
Intuitively one would think that giving 5-HTP
increases urinary serotonin levels, this is not
true. In 2008 the chairman of the research
committee of the University of Minnesota Medical
School wrote a paper based on the research work
of NeuroResearch Clinics specifically noting in
that analysis of urinary
neurotransmitter testing revealed no
correlation between 5-HTP and urinary serotonin.
Serotonin
and dopamine exists is two states "the
endogenous state" found when people are taking
no serotonin and dopamine nutrients and "the
competitive inhibition state" found when people
are taking serotonin and dopamine nutrients.
These two states have no correlation. There is no correlation with baseline
neurotransmitter testing and neurotransmitter testing performed when taking significant
amounts of serotonin and dopamine nutrients. |
